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Recently, a # Pain is a danger signal of herpes zoster # boarded a hot search in Weibo, causing everyone’s attention to herpes zoster!
How painful is it to get herpes zoster? People who have had this disease are worried about it and complain bitterly!
What disease is herpes zoster?
Herpes zoster is what people call "raw snake", "waist-wrapped dragon" and "waist-turned dragon", which is infected by varicella-zoster virus and occurs in middle-aged and elderly people over 50 years old, showing clustered blisters.
At the time of eruption, the skin of the affected area first appeared tidal erythema, then appeared clustered papules without fusion, and then quickly turned into blisters, with redness around the blisters. Skin lesions are often distributed along a certain peripheral nerve area, generally occurring on one side of the body and not exceeding the midline. Blisters will then dry up, scab and fall off, and there may be pigmentation left behind. Generally, skin lesions last for 2-3 weeks, and the elderly are about 3-4 weeks.
Characteristics of herpes zoster-high infection rate.
According to public information, herpes zoster is more common in older people with immunosuppression or immunodeficiency. According to Professor Chang Jianmin, director of the dermatology department of Peking Hospital and deputy director of the Department of Dermatology and Venereology of Peking University, in China, about 99.5% of adults aged 50 and above are latent varicella-zoster virus, and there are about 1.56 million new cases of herpes zoster in people aged 50 and above every year. According to the China Expert Consensus on Diagnosis and Treatment of Postherpetic Neuralgia, the annual incidence of herpes zoster is about 3-5‰.
Characteristics of herpes zoster-patients have to bear great pain.
It is understood that the onset of herpes zoster is very painful, such as cutting, burning, electric shock and whipping. The degree of pain is higher than that of childbirth, and even some patients will suffer from inattention, disorder, anxiety and depression, which is both physical and psychological. Some netizens commented: "Once you get sick, it invades your nerves and hurts like hell."
Often accompanied by significant neuralgia.
There is a saying: "snake sores, waist-wrapped dragons, crawling all over the circle will kill people", which means that it is painful when it comes on. It affects work during the day and sleep at night. Herpes zoster is contagious, mainly through droplets and contact.
Recently, with the increase of rain and the arrival of humid weather, the resistance of middle-aged and elderly people is extremely easy to decline, and herpes zoster is also prone to high incidence. Everyone must pay attention to it.
Vaccination can effectively prevent
Herpes zoster vaccine, namely recombinant herpes zoster vaccine (CHO cell), was officially launched in China in early July 2020. It is suitable for preventing herpes zoster. The vaccination target is adults aged 50 and over, and the immunization program is 2 doses.
Vaccination interval is 2 months, and the longest is no more than 6 months. Experts say that herpes zoster is a common disease in the elderly. To prevent the occurrence of herpes zoster, the first is to improve immunity, and the second is very important for middle-aged and elderly people to get a rash vaccine!
For friends over 50 years old, it is recommended to vaccinate against herpes zoster, because with the increase of age, the probability of herpes zoster is getting higher and higher, and the incidence rate of people over 50 years old is obvious because of the gradual decline of cellular immune function, and active vaccination can reduce this risk. Vaccination is more recommended for people over 50 years old who have had chickenpox and their immunity is relatively low.
Do people who have had it still need to be vaccinated?
Experts say that people who have had herpes zoster once have a very low chance of getting sick again. The human body has a memory of herpes zoster virus immunity and will produce antibodies to avoid getting sick again.
However, people who have had herpes zoster and have relapsed still exist. Such patients often have very low immunity. After getting herpes zoster for the first time, they did not get enough antibodies. Therefore, when a similar situation occurs for the second time, the antibodies in the body are not enough to resist the virus, which will make the disease happen again. Therefore, for patients who have experienced herpes zoster recurrence, experts still recommend vaccination against herpes zoster to prevent recurrence.
Domestic listing enters countdown.
Throughout the world, there are two kinds of herpes zoster vaccines listed. Among them, shingrix from GlaxoSmithKline was approved to be listed in China in 2019 for preventing herpes zoster in adults aged 50 and over, and was officially launched in China market on June 28th, 2020, which is the only herpes zoster vaccine listed in China at present.
As herpes zoster vaccine belongs to the national immunization program, patients need to pay for it themselves. The price announced by Shanghai CDC is 1603.5 yuan/dose, and the full vaccination price is 3207 yuan, which is also the general price of community centers around the world, and the vaccination fee is not cheap. It is worth noting that at present, many domestic pharmaceutical companies are researching and developing the distribution of herpes zoster vaccine, and the fastest research and development company has received the Acceptance Notice of the application for the marketing license of live attenuated herpes zoster vaccine issued by the Drug Evaluation Center of China Food and Drug Administration. In other words, the vaccine has entered the stage of applying for marketing!
Source of this article: CCTV