Xinhuanet Beijing, July 31 ST (Yan Yuxi) The supervision of the third-party payment industry has been increasingly strengthened. On the 30th, official website, the People’s Bank of China, announced the "fines" for two payment companies, with a total penalty of nearly 35 million yuan.
Reproduction of tens of millions of tickets
The punishment results of the central bank on Kayou Payment Service Co., Ltd. (hereinafter referred to as Kayou Company) and Fulinmen Payment Co., Ltd. (hereinafter referred to as Fulinmen Company) show that Kayou Company was fined a total of 25.825 million yuan and Fulinmen Company was fined a total of 8.923 million yuan, and both companies were given warnings.
According to the statistics of the reporters, some of the problems existing in the two payment institutions focus on the risk of acquiring bank cards. According to the announcement that night, the central bank conducted law enforcement inspections on the payment and settlement business of the above two companies from October 2017 to January 2018. It has been verified that Kayou Company has violated the regulations on acquiring transaction information management, acquiring outsourcing business management, reserve fund management, change management, retaining sensitive information of bank cards, failing to implement the on-site inspection system of merchants, and violating the regulations on setting up acquiring settlement accounts.
In addition, Kayou Company was also found to have irregularities such as failing to completely keep the transaction records as required, seriously violating the regulations on the management of real-name system of merchants, and passively cooperating with the inspection and supervision of the People’s Bank of China.
In addition to the violations similar to those of card friends, Fulinmen Company also has problems such as violating the relevant provisions of fund settlement and risk monitoring management.
At the same time, the central bank also requires that in order to prevent financial risks, two non-bank payment institutions withdraw from the bank card acquiring business in serious violation areas in an orderly manner within one year. Kayou Company withdrew its bank cards from Guizhou, Hainan, Gansu, Hebei, Liaoning, Heilongjiang, Zhejiang, Hunan, Jilin, Ningxia, Chongqing, Anhui, Guangdong (excluding Shenzhen), Guangxi, Shanghai, Jiangxi, Shaanxi, Jiangsu, Inner Mongolia, Shanxi, Hubei, Xinjiang, Fujian, Henan and Tibet. Fulinmen Company withdrew from the bank card acquiring business in Sichuan Province.
It is understood that Kayou Company was established in 2003, formerly a holding subsidiary of China UnionPay, and it is a financial payment service enterprise. In 2009, the company carried out share reform, with a registered capital of 100 million yuan. On June 27, 2012, Kayou Payment obtained the administrative license from the People’s Bank of China, allowing it to carry out bank card acquiring business nationwide. Founded in 2009, Fulinmen Company is an offline payment business brand of Shanghai Deyi Network Technology Co., Ltd., a subsidiary of Defeng Network Co., Ltd., with a registered capital of 100 million yuan, and was granted a payment business license by the People’s Bank of China on December 22, 2011.
It is not limited to this, and the categories of violations in cross-border payment have recently been on the "list" of regulatory penalties for many times. For example, on May 15th, Shenzhen Central Sub-branch of the People’s Bank of China confiscated about 11.08 million yuan of illegal income from Zhifu Electronic Payment Co., Ltd., and imposed a fine of about 14.53 million yuan. The total amount of fines and confiscations was about 25.61 million yuan, which was huge.
It is worth noting that before this, Shenzhen Branch of the State Administration of Foreign Exchange paid a fine of 15.908 million yuan to Zhifu. The violations included: evasion of foreign exchange in violation of foreign exchange account management regulations, and failure to submit financial and accounting reports, statistical statements and other materials as required.
100% deposit will be realized for the reserve fund of the payment institution.
In fact, since the central bank issued the Notice on Standardizing Payment Innovation Business (No.281 Document) in December last year (hereinafter referred to as the Notice), the relevant policies for rectifying third-party payment have formed a momentum of intensive release, and they have been put into practice in the first half of 2018.
This is not only reflected in the "iron fist" punishment policy for enterprises that violate the rules, but also includes the full payment of the third-party payment institutions’ reserves.
On June 29th, the central bank issued the Notice on Relevant Matters Concerning the Centralized Deposit of All the Customer Reserves of Payment Institutions (Yin Ban Fa [2018] No.114), requiring that the proportion of centralized deposit of customer reserves of payment institutions be gradually increased every month from July 9th, 2018, and 100% centralized deposit be realized by January 14th, 2019.
"Reserve fund", that is, non-bank payment institutions receive their customers’ monetary funds to be paid in advance, does not belong to the payment institutions’ own property, but enjoys its interest income because it is controlled by the payment institutions. Insiders pointed out that it is precisely because of the separation of ownership and control that moral hazard is easily induced — — That is, the risk of misappropriating the reserve fund or even running away with the money, with the expansion of the transaction scale generated by third-party payment institutions, the deposit and management of this part of the funds is also imminent.
In January 2017, the central bank issued the Notice on Relevant Matters Concerning the Implementation of Centralized Deposit and Management of Customer Reserves of Payment Institutions, which stipulated that from April 17, 2017, payment institutions should deposit customer reserves into the special deposit account of designated institutions according to a certain proportion, and the funds in this account will not pay interest for the time being.
The central bank has raised this ratio several times since then. On the occasion of 2017 and 2018, the central bank issued a notice saying that from 2018, the centralized deposit ratio of payment institution customers’ reserve funds will increase from the current 20% to about 50%.
Then, on June 29th, the central bank issued a notice saying that the centralized deposit ratio of customers’ reserves of payment institutions would be gradually increased to 100%, which also reflected the gradual arrangement in the implementation time of the policy.
In the eyes of many people in the industry, the strong regulatory situation of the third-party payment industry may continue. The central bank said that in the next step, it will continue to strengthen the supervision of the payment and settlement market in accordance with relevant laws and regulations, severely punish illegal acts of payment and settlement, and ensure the sustained, stable and healthy development of the payment market.
Xinhua News Agency, Beijing, December 26 (Reporter Gao Jing) Since the beginning of this year, China has continued to promote the blue sky defense war, and the air pollution control in key areas has achieved remarkable results, but the air quality in some areas has fluctuated, and the concentration of PM2.5 has increased to varying degrees.
At the press conference held by the Ministry of Ecology and Environment that day, Liu Youbin, spokesperson of the Ministry of Ecology and Environment, introduced this situation.
Liu Youbin said that air pollution control in key areas has achieved remarkable results. According to the latest data from the Ministry of Ecology and Environment, in November this year, the average number of excellent days in "2+26" cities in Beijing, Tianjin and Hebei and surrounding areas was 63%, up 18.6 percentage points year-on-year; The concentration of PM2.5 was 63 μ g/m3, a year-on-year decrease of 25.9%.
He said that in addition to key areas, the quality of atmospheric environment in other areas has also improved significantly. From January to November 2019, the average concentration of PM2.5 in 261 cities with PM2.5 below the standard level and above was 38 μ g/m3, which was 22.4% lower than that in the same period of 2015, exceeding the progress requirements of the 13 th Five-Year Plan. Among them, Central China and Southwest China decreased by 22% and 13% respectively; The average concentration of PM2.5 in more than a dozen provinces such as Yunnan, Guizhou, Guangdong, Zhejiang, Heilongjiang and Inner Mongolia changed from substandard to standard.
He also said that since the beginning of this year, air quality in some areas has fluctuated due to factors such as insufficient work pressure transmission and ineffective response to heavy polluted weather. For example, in the border area of Jiangsu, Anhui and Lu Yu where the "2+26" city and the Yangtze River Delta meet, the concentration of PM2.5 in Hunan and other places has increased to varying degrees.
In response to the above situation, the Ministry of Ecology and Environment timely organized a symposium on air quality early warning and joint prevention and control of regional air pollution, carried out air quality early warning on a quarterly basis, and interviewed areas with serious pollution rebound. At present, the rebound of pollution in some areas has been effectively curbed.
Liu Youbin said that in the next step, the Ministry of Ecology and Environment will continue to guide all localities to accurately control pollution, scientifically control pollution, and control pollution according to law to ensure the successful completion of the goals of the blue sky defense war. The first is to implement the working mechanism of "early warning, interview and accountability" and carry out special inspections in areas where air quality has deteriorated significantly and the progress of binding indicators has lagged behind. The second is to strengthen guidance and assistance to cities in non-key areas, and strengthen regional joint prevention and control of cross-regional pollution problems. The third is to strengthen the response to heavy pollution weather, guide local governments to implement performance grading and differentiated control, and effectively reduce the impact of heavy pollution weather.
As double 11 approaches, many people have already filled their shopping carts with health care products in advance, just waiting for the zero discount time to start shooting. Among them, one of the hottest and most publicized commodities is probably imported joint health care products. However, the latest research proves that the key ingredients in joint health care products may not be as useful as placebos. At the same time, because its formula changes at will, its medicinal properties and toxicity are also difficult to monitor. Friends who want to buy such health care products at special prices need to think twice before you do.
Today’s two articles bring together some kinds of goods that should be bought carefully or even not. Among them, the e-cigarettes that we strongly warned about were completely removed from Taobao and Tmall on November 6. So far, the online sales platform has completely banned the sale of e-cigarettes.
Writing | Shi Juan
Maybe you exercise a lot, maybe you need to sit still for a long time because of your work, or maybe you are old. In either case, the concept of protecting your joints must be familiar.
Known as a health care product that is good for joints, the most popular brand at present is Move Free, which is a brand of Schiff, a famous American health care company. Common models are as follows:
Image from Schiff official website
Costco, a famous American supermarket, also has several kinds that people often buy.
Image from CVS official website
The main components of these drugs are glucosamine and chondroitin sulfate. Some of them are added with vitamin D or an organic sulfur compound: dimethyl sulfone (MSM, an essential substance for human collagen synthesis).
Glucosamine claims to "strengthen, protect and rebuild joints", while chondroitin sulfate "can help lubricate and cushion joints", thus finally relieving joint pain, joint stiffness and arthritis.
I believe everyone has read many online articles recommending this health care product (the screenshot is omitted here).
However, are glucosamine and chondroitin sulfate really good for joints?
One study after another published in authoritative magazines shows that glucosamine and chondroitin sulfate health care products have no effect on joints. Even in the United States, there are several class actions, accusing the manufacturers of these health care products of making false advertisements, misleading and deceiving ordinary consumers [1, 2].
Photo: In June 2019, consumers collectively sued Schiff Move Free for false advertising and formally filed a case. [2]
A series of studies, the answer is getting clearer and clearer.
The most famous research is called Gait (Glucosamine/Chondroitin Arthritis Intervention Trial), which took four years and cost $12.5 million. It was funded by two departments under the National Institutes of Health (NIH), namely National Center for Complementary and Alternative Medicine (NCCAM) and National Institute of Arthritis/Musculoskeletal/Dermatology (NIAMS).
The purpose of this study is to determine whether glucosamine and chondroitin sulfate are effective in the treatment of osteoarthritis.
Let’s take out these studies and analyze them for everyone.
one
This study was published in the authoritative medical journal New England Medicine in 2006 [3].
A total of 1583 patients with osteoarthritis were recruited and randomly assigned to take:
Placebo (the same shape as medicine, but without the ingredients of medicine, it can be simply understood as sugar ball)
1,500 milligrams of glucosamine per day
1200 mg chondroitin sulfate per day
1500 mg glucosamine +1200 mg chondroitin sulfate per day
200 mg of prescription drug celebrex (an analgesic used to relieve pain for arthritis and other diseases) every day.
It is worth noting that this dose is the dose of glucosamine and chondroitin sulfate in popular health care products at that time. It is emphasized here that there was a reason for the dose in health care products at that time, which will be further explained later.
If the patient feels that the joint pain is still uncontrollable, he can take up to 4000 mg of acetaminophen (the main component of Tylenol) every day.
The main purpose of the study is to see if the pain in the knee joint is reduced by 20% after taking the medicine for 24 weeks.
The result is as follows:
It can be seen that there is no significant difference between the group taking glucosamine and chondroitin sulfate and the placebo group.
However, it is worth noting that at 24 weeks, 60.1% (more than half) people who took placebos also felt that their symptoms had improved. This extraordinary placebo effect is often seen in clinical trials of arthritis. Without knowing what they are eating, patients think they are taking useful drugs, and strong psychological hints will make the pain less intense.
Source: The-Science-Site.com.
This trial is a good example to explain why clinical trials are rigorous only if they are randomized and double-blind. Randomized double-blind trials should make sure that there is basically no difference in appearance between the pills in the placebo group and the real pills. The people who eat them can’t guess what they are eating at all, and the people who collect data don’t know what each patient is eating, so as to ensure that there will be no bias in the data collection process.
After taking celebrex for 24 weeks, those who felt that their pain was reduced by 20% were about 10% higher than those in the placebo group, achieving a statistically significant effect. Once again, it proves that this prescription drug is effective.
Finally, the author of this study divided the patients into groups according to the severity of symptoms, and found that the combined therapy of 1500 mg glucosamine and 1200 mg chondroitin sulfate/day seems to have certain effect on patients with severe symptoms. However, it is worth noting that the number of volunteers with severe symptoms in this study is relatively small, and the sample size is too small to be conclusive, which needs further research to confirm.
2
So, these authors continued to study. The new results were published in the journal Arthritis and Rheumatism in 2008 [4]. We call it study 2 (the last one was called study 1).
The time of the second study was extended from 24 weeks to 24 months (two years), and the patients with severe symptoms were studied emphatically, because the last short-term trial found that the combination therapy of glucosamine and chondroitin sulfate might be useful for these patients.
572 patients with moderate or severe knee osteoarthritis were recruited and randomly divided into five groups:
placebo
Glucosamine (500 mg each time, 3 times a day: 1500 mg/day)
Chondroitin sulfate (400 mg each time, 3 times a day: 1200 mg/day)
Glucosamine (500 mg each time, 3 times a day)+chondroitin sulfate (400 mg each time, 3 times a day)
Celebrex (200 mg once a day)
The final effective index of this experiment is not the subjective pain feeling in the first experiment (this kind of patient’s feeling is the most prone to error), but the change of joint space width is determined by X-ray at 24 months. The more severe osteoarthritis is, the more cartilage loss is, and the smaller joint space is. If a drug can stop or even reverse the shortening of joint space, it can improve the joint structure and relieve symptoms.
Finally, in the second study, the average joint spacing of patients with osteoarthritis in the placebo group decreased by 0.166 mm after two years, which meant that osteoarthritis was aggravated.
Compared with placebo, glucosamine, chondroitin sulfate or their combination therapy did not significantly reduce the loss of joint space width (arthritis did not relieve).
The researchers even observed that the joint space shortening (arthritis aggravation) of combined therapy was more serious than that of other groups, probably because taking two drugs at the same time affected the absorption of each drug-and most health care products on the market mixed these two ingredients together.
three
The final result of the GAIT study was published in Rheumatology Annual Report in 2010 [5]. We call it study three.
The third study was similar to the first study, except that the experiment was extended from 24 weeks to 24 months.
This time, the researcher recruited 662 volunteers with moderate to severe osteoarthritis and randomly divided them into five groups as in the second paper. The main index is, as in the first study, to see whether the pain of knee joint is reduced by 20% compared with that before taking medicine.
The results of this long-term experiment are similar to those of study 1. All groups had significant pain and functional improvement within 2 years. However, no treatment is significantly better than placebo. There was no statistically significant difference between the treatment groups, which once again proved the powerful placebo effect.
The good news is that no serious side effects were observed in all the treatment groups-it seems that these drugs are safe to take for at least two years in this experiment.
GAIT research tells us:
1. The curative effect of glucosamine and chondroitin sulfate comes from strong psychological suggestion to a great extent. Even if you eat "sugar balls", if you think you are eating drugs that are useful for joints, more than half of people will feel that joint pain is reduced.
2. Taking glucosamine and chondroitin sulfate at the same time may affect the absorption of any single component.
3. Glucosamine and chondroitin sulfate can not improve the shortening of joint space after illness.
four
The latest study on glucosamine and chondroitin sulfate was completed in 2016 [6]. This experiment recruited 164 patients with knee pain caused by osteoarthritis, and half of them took glucosamine (1500 mg/day) and chondroitin sulfate (1200 mg/day). The other half took a placebo.
However, the study was terminated early for an unusual reason: compared with the placebo group, the symptoms of patients who took glucosamine and chondroitin sulfate worsened.
Further than the previous three experimental results, this result suggests a terrible possibility: taking glucosamine and chondroitin sulfate may make the joint condition worse than doing nothing.
Move Free, hepatotoxicity?
I often hear friends around me say that most people eat health care products without any side effects. What if they eat them? If you don’t eat, don’t you miss that "one thousand" opportunity?
However, have you overlooked the "one thousand" harmful situation?
In fact, there are no published prospective studies on the efficacy, tolerance and safety of most health care products.
Remarks:
Prospective study usually involves observing a group of subjects for a long time, and studying whether some observed results (such as illness) are related to other factors (such as suspicious risks or protective factors) during the trial. The prospective study related to the safety of health products mentioned here is to observe whether a group of people who eat health products will have some adverse reactions related to eating health products.
This is because the ingredients of health care products are not strictly monitored by FDA, and the formula can be changed frequently. This not only makes it difficult to study its security, but also means that its security is even more insecure. Who knows which batch of formula will go wrong?
Take the current Schiff Move Free series products as an example.
If you look closely at the website of Schiff Nutrition International, the manufacturer of Move Free, you will find that there is a small line below:
“Our packaging and/or formulas change from time to time. Please refer to the actual packaging for current product information.”
Our packaging and/or formula will change from time to time. Please refer to the actual packaging for current product information. "
Figure: Composition description of a Move Free product on Schiff Nutrition International website.
At present, many cases have been reported, saying that patients taking Move Free have obvious liver damage in clinic.
In 2010, the first case report on liver injury caused by taking Move Free was published in the United States [7]. Subsequently, new cases were reported in August 2012 and September 2013. In these published cases, patients developed acute hepatocyte injury within 1-3 weeks after taking a Move Free product. The degree of injury is moderate and can be relieved within 1 to 2 months after stopping taking it; There is no immune allergy and autoimmune reaction, and it can finally recover completely in all cases. However, one patient resumed using the product when he was half well, and immediately developed acute liver injury with similar symptoms. In addition, although no more cases have been published, there are three prospective studies on drug-induced hepatotoxicity in the United States, all of which mentioned acute liver injury cases related to Move Free, all of which occurred in 2012-2013 [October 12].
The specific Move Free products mentioned in these cases at that time, in addition to the main glucosamine and chondroitin sulfate, also contained a patented herbal mixture, including China Scutellaria baicalensis and Acacia catechu.
These reports attributed the liver injury caused by Move Free to Scutellaria baicalensis Georgi in China [13], and only one case was attributed to glucosamine [11]. However, China Scutellaria baicalensis Georgi protects the liver in animal models, but not damages it [14-16]. Why can it cause human liver injury? The report did not reasonably explain its mechanism of liver injury. There is also a kind of explanation that the China Scutellaria baicalensis Georgi in Move Free contains pollutants, or maybe it is not China Scutellaria baicalensis Georgi at all (the manufacturer made a mistake and added a similar plant as China Scutellaria baicalensis Georgi).
Therefore, it is still uncertain what specific components may cause liver injury. Manufacturers often change the composition and concentration of health care products, so it is not certain whether the products currently on the market still contain these harmful ingredients. At present, Move Free series products no longer list "including China Scutellaria baicalensis Georgi and other herbal ingredients", but give a patented ingredient with a new name on some products, which is called "uniflex (fruitex-b calcium fruitoborate)", claiming to be a mineral extracted from vegetables and fruits.
What’s more noteworthy is that the content of chondroitin sulfate in the Move Free series products listed on the official website in the United States has been greatly reduced (see the figure below), and the dosage has been reduced from 1200mg per day to 200mg per day. There is no glucosamine and chondroitin sulfate in the Move Free Ultra series products, one of which only contains calcium and calcium borate, and the other contains a patented cartilage mixture. However, most of them are produced by different manufacturers, such as similar products of Kirkland brand sold by Costco, and the dosage is still 1500 mg of glucosamine and 1200 mg of chondroitin sulfate every day.
Figure: The ingredients of four existing Move Free series products (from official website, USA) are chondroitin sulfate content in the red box. Click to see a bigger picture.
Figure: Components of four existing Move Free Ultra series products (from official website, USA).
In addition, a small study in 2013 found that taking glucosamine may increase the risk of glaucoma, which will threaten vision if it is not treated in time [17]. Chondroitin sulfate can play the role of blood anticoagulant, so it may cause internal bleeding.
Another problem that is often overlooked is drug interaction: any combination of compounds may produce bad interactions. If you are taking other drugs, you must decide carefully whether to take health care products. Because they may not contain the amount indicated on the label, or they may contain pollutants-this will make it more difficult for you to accurately judge whether there will be drug interactions.
Other side effects of glucosamine and chondroitin sulfate include:
Heartburn, heartburn
feel tired and sleepy
headache
Allergic reaction (especially if you are allergic to shellfish)
What drugs/treatments are there for arthritis?
So far, there is no therapy or medicine that can cure arthritis.
There are many drugs that can be used to improve symptoms (mainly to relieve pain) and slow down the deterioration of the disease, but they cannot completely reverse the structural damage.
Because there are more than 100 different kinds of arthritis, each specific type of treatment is not exactly the same. We should prescribe the right medicine after diagnosis.
After the doctor looked around and guessed the type of arthritis he might have, there were two main methods for further diagnosis:
1. Body fluid analysis. Analyzing blood, urine and joint fluid can help determine what type of arthritis you may have. In order to obtain a sample of joint fluid, doctors usually need to put a needle into the joint space to suck some fluid.
2. Imaging analysis. Commonly used imaging methods include X-ray, CT, magnetic resonance imaging (MRI) and ultrasound.
After confirming the type of arthritis, you may need to try several different treatments or combinations of treatments to find the one that suits you best.
There are usually three types of therapies: drugs, physical therapy and surgery.
01
medicine
Different types of arthritis, should use different drugs. Commonly used arthritis drugs include:
Analgesics These drugs help to relieve pain, but they can’t diminish inflammation. For example, acetaminophen (the main component of Tylenol), Ultram (Ultracet), and some strictly regulated painkillers (such as oxycodone).
Non-steroidal anti-inflammatory drugs (NSAIDs). These drugs can relieve pain and diminish inflammation at the same time. Over-the-counter NSAID include ibuprofen (Motrin) and naproxen sodium (Aleve). Some types of NSAID must be obtained by prescription. Oral NSAID may cause stomach upset, and some may increase the risk of heart attack or stroke. Some NSAID can also be rubbed on joints as creams or gels. I have talked about the points for attention in the use of Tylenol and Ibuprofen before. If you are interested, you can go and see it (→ How to use Tylenol and Ibuprofen correctly? | 117 threesome).
Anti-irritant Some kinds of ointment contain menthol or capsaicin. Rubbing these ointments on the skin of painful joints may interfere with the transmission of pain signals, thus achieving the effect of relieving pain.
Antirheumatic drugs. Usually used to treat rheumatoid arthritis, it can slow down or prevent the immune system from attacking joints. Such as methotrexate (Trexall) and hydroxychloroquine.
Specific immune response modulators. It is usually used with anti-rheumatic drugs, which target certain protein molecules involved in immune response. Such as etanercept (Enbrel) and infliximab (Remicade).
Corticosteroids. These drugs, including prednisone and cortisone, can reduce inflammation and suppress the immune system. Corticosteroids can be administered orally or directly into joints.
02
physiotherapy
Physical therapy is helpful for some types of arthritis. Moderate exercise can improve and strengthen the muscles around the joints.
03
operation
If nothing works, it will be operated. Include joint repair or joint replacement.
04
Acupuncture, yoga, Tai Ji Chuan and massage.
There is little data to support these unconventional treatments, but there is no conclusive evidence that they are ineffective. You can look at your own reaction to see if you try.
Total knot
Although there is no convincing data to prove that health products containing glucosamine and chondroitin sulfate are beneficial to joints, many people will buy and take them. Some people think that even if there is no effect from the overall data of the population, it may be useful for individuals because of some factors; Others believe that even if most of the effects come from the placebo effect, the benefits of the placebo effect are real and hard to give up.
However, the latest clinical results and several cases of side effects show that these health care products may also be harmful to health. Manufacturers often change the formula, and the actual ingredients and dosage may be far from what you expected.
Most types of arthritis are chronic and will affect life-long diseases. Knowing all kinds of risk factors (including obesity, sedentary lifestyle, eating habits, joint injuries, smoking, etc.), changing lifestyle and reducing the chance of getting sick are the best preventive measures. It is absolutely unacceptable to put all your hopes on health care products without fundamentally changing your living habits.
[3] D. O. Clegg et al., Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis. N Engl J Med 354, 795-808 (2006).
[4] A. D. Sawitzke et al., The effect of glucosamine and/or chondroitin sulfate on the progression of knee osteoarthritis: a report from the glucosamine/ chondroitin arthritis intervention trial. Arthritis Rheum 58, 3183-3191 (2008).
[5] A. D. Sawitzke et al., Clinical efficacy and safety of glucosamine, chondroitin sulphate, their combination, celecoxib or placebo taken to treat osteoarthritis of the knee: 2-year results from GAIT. Ann Rheum Dis 69, 1459-1464 (2010).
[6] J. A. Roman-Blas et al., Combined Treatment With Chondroitin Sulfate and Glucosamine Sulfate Shows No Superiority Over Placebo for Reduction of Joint Pain and Functional Impai rment in Patients With Knee Osteoarthritis: A Six-Month Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Arthritis & Rheumatology 69, 77-85 (2017).
[7] S. A. Linnebur, O. C. Rapacchietta, M. Vejar, Hepatotoxicity associated with chinese skullcap contained in Move Free Advanced dietary supplement: two case reports and review of the literature. Pharmacotherapy 30, 750, 258e-262e (2010).
[8] L. Yang, A. Aronsohn, J. Hart, D. Jensen, Herbal hepatoxicity from Chinese skullcap: A case report. World J Hepatol 4, 231-233 (2012).
9. R. Dhanasekaran, V. Owens, W. Sanchez, Chinese skullcap in move free arthritis supplement causes drug induced liver injury and pulmonary infiltrates. Case Reports Hepatol 2013, 965092-965092 (2013).
[10] V. J. Navarro et al., Liver injury from herbals and dietary supplements in the U.S. Drug-Induced Liver Injury Network. Hepatology (Baltimore, Md.) 60, 1399-1408 (2014).
[11] S. Rossi, V. J. Navarro, Herbs and Liver Injury: A Clinical Perspective. Clinical Gastroenterology and Hepatology 12, 1069-1076 (2014).
[12] N. Chalasani et al., Features and Outcomes of 899 Patients With Drug-Induced Liver Injury: The DILIN Prospective Study. Gastroenterology 148, 1340-1352.e1347 (2015).
[13] V. J. Navarro, L. B. Seeff, Liver Injury Induced by Herbal Complementary and Alternative Medicine. Clinics in Liver Disease 17, 715-735 (2013).
[14] Q. Dong et al., Scutellaria baicalensis Georgi extract protects against alcohol?induced acute liver injury in mice and affects the mechanism of ER stress. Mol Med Rep 13, 3052-3062 (2016).
[15] J. Boer et al., Protection against aflatoxin-B-1-induced liver mutagenesis by Scutellaria baicalensis. Mutation research 578, 15-22 (2005).
[16] H. N. Thanh et al., Ethanol extracts of Scutellaria baicalensis protect against lipopolysaccharide-induced acute liver injury in mice. Asian Pacific Journal of Tropical Biomedicine 5, 761-767 (2015).
[17] R. K. Murphy et al., Oral Glucosamine Supplements as a Possible Ocular Hypertensive Agent. JAMA Ophthalmology 131, 955-957 (2013).
The pen name is "Cats at My Will" and now lives in Boston, USA. I graduated from the Department of Biological Sciences and Technology in Tsinghua University with a bachelor’s degree, and joined a multinational well-known pharmaceutical company to engage in drug research and development after obtaining a doctorate in the United States. For more than ten years, he led the team to fight diabetes and muscular dystrophy. In recent years, he focused on the research and development of anti-aging drugs. Personal WeChat WeChat official account "Feel Free" to talk to you about medical care.
Shi Juan
END
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Original title: "double 11 carefully buys joint health products: the formula is changed at will, and the effect is not as good as placebo | 117 threesome"
Recently, fraud cases caused by AI face-changing technology have attracted people’s attention. With the development of AI model, the application scope of "face changing" technology is getting wider and wider, and the breakthrough of technology also makes the facial expressions and action details of the characters after face changing more realistic, which may bring serious harm once it is used by criminals. The reporter’s investigation found that it is very easy to obtain AI face-changing software on the Internet. Where is the legal boundary of using AI face-changing software? How to supervise beforehand?
Paid AI face-changing software appears on the network.
Package prices range from 499 yuan to 2888 yuan.
At present, relying on the breakthrough of large models and algorithms, AI face-changing is realizing a wider range of applications, causing more concerns. On the internet, there are many tutorials demonstrating the use and effect of face-changing software. Different from a large number of free software that gives ordinary people "early adopters", the reporter found that there are many high-priced paid AI face-changing software on the Internet. What is the difference between these paid software and free software?
The reporter contacted a developer after searching for "AI face-changing software", and he provided the reporter with a demonstration video of using his software to realize face-changing. On the left side of the dual-window page is the original video before face-changing, and on the right side is the video after face-changing. To the naked eye, the mouth shape, expression and tiny movements of the "digital man" after face-changing are almost flawless.
△ The face changing effect of the amateur shown by the seller (S is the original video, D is after the replacement)
On its sales website, the software developer also showed how to stitch the eyes and mouths of two famous actresses together to generate a new "digital man" video.
△ Local facial features replacement displayed by the seller
This paid software offers different versions from basic (LV1) to super (LV4) to full set (LV5). For the primary package, 499 yuan provides software interface, video guidance, face changing model, etc. If 2888 yuan is spent, you can get a full set of (LV5) video face changing models.
△ There are many different levels of face-changing software products available on the network.
"You can change your face if you want."
AI big model can integrate multiple functions to create a "digital person"
Open the website, there is no text at the bottom showing that it has been filed. The seller is also very cautious, and only uses words to communicate throughout. He said that compared with the basic (LV1) to super (LV4) packages, the full (LV5) version has more iterations and stronger capabilities, which can also be understood as a more realistic face-changing effect. At the same time, it can not only realize video face-changing, but also support live face-changing.
The reporter further asked, can you change your face according to your own needs? Software developers said: "What kind of face you want to change can be trained with material."
△ Software developers are chatting with reporters.
A technician engaged in AI development said that this means that there may be more uncontrollable risks. "AI face-changing technology like deepfake is open source. Recently, the AI ? ? big model has become popular, and its algorithm has been updated. It is possible to integrate the functions of Wensheng map, Wensheng text, Wensheng audio, Wensheng video and face-changing. By combining these functions, a completely new’ digital person’ or’ AI person’ can be created, and the cost and difficulty of supervision are several orders of magnitude higher."
△ User feedback displayed by the seller
Expert: An Effective Supervision System for Labeling
Can clarify the fuzzy boundary brought by AI face change in advance.
Zhao Zhanling, a lawyer and IT legal expert of Beijing Jiawei Law Firm, said that from the perspective of post-strike, there are provisions on fraud in the criminal law; It is clear in the Civil Code that citizens have the right to portrait, name, reputation and other corresponding civil rights. In other words, if there is a related case of fraud by using someone else’s portrait, the criminals can be bound and sanctioned by law afterwards. However, with the rapid development of artificial intelligence technology, we should also explore how to effectively prevent beforehand.
For example, in the Regulations on the Management of Deep Integration of Internet Information Services, it is required that if the deep integration service may lead to confusion or misidentification by the public, the deep integration service provider shall prominently mark the reasonable position and area of the generated or edited information content.
The Measures for the Administration of Generative Artificial Intelligence Services (Draft for Comment) requires that before using generative artificial intelligence products to provide services to the public, a safety assessment should be reported to the national network information department in accordance with relevant regulations; Respect the legitimate interests of others; Product providers should be responsible for the legality of pre-training data and optimizing the source of training data for generative artificial intelligence products.
△ Source: vision china
Pan Helin, co-director of the Digital Economy and Financial Innovation Research Center of the International Joint Business School of Zhejiang University, believes that at present, if the requirements of the logo can be effectively implemented and an effective supervision system can be formed, the fuzzy boundary brought by the AI ? ? face change can be clarified in advance to a great extent.
Pan Helin: At present, the supervision system of AI face-changing logo has not yet been formed. It is necessary to identify the unlabeled content through technical means, and there must be specific punishment measures, standards and systems for unlabeled individuals or units.
Zhao Zhanling believes that in the long run, the supervision and punishment measures need to be "iterated" with the development of technology to form a three-dimensional and effective governance plan.
A few days ago, we learned from Tengshi official that Tengshi’s medium and large MPV——2025 will be listed on December 26. It is reported that the appearance of the new car is basically the same as the cash, but there will be no small upgrade in configuration.
In terms of details, a laser radar is installed above the roof of the 2025 Tengshi D9, which is expected to be greatly improved in terms of intelligent driving; In addition, the "DM-I AWD" logo is added to the rear logo. In terms of size, the length, width and height of the new car are 5250×1960×1900mm and the wheelbase is 3110mm respectively.
The interior of the new car is a highlight of the 2025 Tengshi D9 upgrade. Although it still continues the overall layout of cash, the new car will be replaced with a new one. It is expected that there will be no small changes in the central island area. In addition, whether the co-pilot is equipped with an entertainment screen is also a hot spot for netizens to pay attention to this upgrade, and more information is still to be announced by the official.
In terms of power, the 2025 Tengshi D9 will be upgraded to the fifth-generation DM technology, equipped with a 1.5T engine+plug-in hybrid system, with a maximum engine power of 115kW and a maximum speed of 190km/h; On the power battery level, the new car will be equipped with a set of 39.938kWh lithium iron phosphate batteries, with pure battery life of 145km and 155km. We will continue to pay attention to the latest news about the 2025 Tengshi D9.
Takeaway riders’ war escalated: riders laugh and users worry, when will the price war stop?
With the development of science and technology, internet giants have set foot in the take-away industry, and the war of take-away riders has escalated. In this highly competitive market, riders laugh, but users are worried. When will the price war stop? This paper will analyze the current competitive situation of the take-away market from a professional perspective and put forward some possible solutions.
First of all, we need to know the advantages of Internet giants such as JD.COM and Meituan in policy, technology and capital, as well as the protection of the rights and interests of take-away riders. In terms of policies, major platforms have introduced policies such as paying five insurances and one gold for riders and canceling the overtime penalty for delivery, aiming at improving the welfare of riders and protecting their rights and interests. In terms of technology, major platforms improve distribution efficiency and reduce costs through artificial intelligence, big data and other technical means. In terms of funds, the major platforms have strong financial strength and can invest more resources to increase market share.
However, the competition in the take-away market is fierce, and the price war has become an important means for major platforms to compete for market share. The price war caused the take-away platform to reduce the profit margin in order to reduce the cost, and then passed the cost on to the settled merchants and users. In order to attract more orders, merchants reduce prices, which leads to further compression of profit margins. At the same time, users have to accept higher prices in order to get more coupons. This vicious circle not only harms the interests of merchants and users, but also brings greater work pressure and safety risks to takeaway riders.
In order to solve this problem, we need to put forward some possible solutions from multiple angles. First of all, the government should strengthen supervision, standardize market competition behavior, and prevent vicious competition from causing market chaos. Secondly, the take-away platform should strengthen its own management, improve distribution efficiency, and reduce the work pressure and safety risks of riders. In addition, the take-away platform can also increase revenue sources and profit margins by increasing delivery rates and introducing third-party payment. Finally, the take-away platform can introduce some preferential policies to attract merchants to settle in and improve their profit margins.
For users, they should look at the competitive situation in the take-away market more rationally, and don’t blindly pursue low prices and ignore quality and service. At the same time, they should also pay attention to their own health and safety issues and choose businesses with high credibility and good service for consumption. For riders, they should strengthen their awareness of self-protection, improve their safety awareness, obey traffic rules and ensure their own safety. In addition, they can improve their welfare and career development prospects by joining trade unions and improving their skills.
To sum up, the take-away market is fiercely competitive, and the price war has become an important means for major platforms to compete for market share. In this highly competitive market, we need to put forward some possible solutions from multiple angles. Measures such as strengthening supervision by the government, strengthening self-management of take-away platforms and introducing preferential policies to attract merchants to settle in will help solve the current predicament of the take-away market. At the same time, users and riders should also strengthen their awareness of self-protection and jointly safeguard market order and consumer rights. Only in this way can we realize the sustainable development of the take-away market.
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Communist party News Network, Beijing, December 13 (Reporter Ethan) The website of Anhui Provincial Commission for Discipline Inspection recently published the confessions of Hu Linjuan, former vice mayor of Ningguo City. Hu Linjuan said in the confession, "On December 1, 2016, I was notified by Xuancheng Supervision Bureau to accept the investigation. When I first came, I vowed that I had no problems, but now it seems that I am not without problems, but there are many and serious violations of discipline. "
Hu Linjuan said that during the 20-odd nights under investigation, she often dreamed of going home to see her mother at night. Her old man said to me the most: "Girl, it is not easy for you to get to today’s leadership position. Don’t take other people’s things." Such a simple truth, until now, I suddenly realized that I failed to keep the bottom line, distorted my values, and slipped further and further on the wrong road.
The full text of the confession is as follows:
Resume:Hu Linjuan, female, born in January 1964, Han nationality, yi county, Anhui Province, holds a postgraduate degree. He joined the work in December 1982 and worked in Ningguo City (county) Taxation Bureau, Audit Bureau, Supervision Bureau and Finance Bureau successively. In January 2003, he served as member of the Standing Committee of Ningguo CPPCC and deputy director of Finance Bureau. In January 2007, he served as vice chairman of Ningguo CPPCC and deputy director of Finance Bureau. From September 2011 to December 2016, he served as deputy mayor of Ningguo Municipal Government (from June 2010 to March 2016) On December 15, 2016, he was removed from the post of deputy mayor of Ningguo Municipal Government.
Processing result:In July 2017, Hu Linjuan was dismissed from public office for violating political discipline, organizational discipline and relevant provisions of national laws and regulations. Her suspected crimes, clues and money involved have been transferred to judicial organs for legal treatment.
Confessions:
I was born in an intellectual family, and my parents are both teachers who teach by example. I am a non-party cadre, who has trained and educated me organizationally, trained me from a grass-roots general tax official to a leading cadre, and let me exercise in multiple departments and positions. In September, 2011, I took the leadership position of deputy mayor of Ningguo Municipal People’s Government, but I didn’t know how to cherish and care. Instead, I used my power for personal gain and regarded my leadership position as an "Shang Fang Sword" to seek personal interests. I ignored the care and concern of the party organization for a non-party cadre, failed the cultivation of the party organization, and failed the reuse of the party organization.
On December 1, 2016, I was informed by Xuancheng Supervision Bureau to accept the investigation. When I first came here, I vowed that I had no problems, but now it seems that I don’t have no problems, but there are many and serious violations of discipline. During the 20-odd days under investigation, with the patient guidance, help and education of the comrades of the investigation team, I reviewed the serious economic problems I had committed and reflected on why I had embarked on this serious violation of discipline. After carefully studying party constitution, the spirit of the series of important speeches by the Supreme Leader’s General Secretary, especially the important exposition on comprehensively and strictly administering the Party and the series of articles on learning, thinking and practicing enlightenment, I deeply reflect and carefully analyze my mistakes and their deep-seated reasons, mainly in the following aspects:
Ignore theoretical study and relax the transformation of world outlook
During the more than 20 days and nights under investigation, I repeatedly asked myself what was wrong and where did it come from? Why do you always think that you are honest, self-disciplined and fair, and you don’t realize that you are on the road to corruption step by step. When I think about it carefully, I usually don’t pay attention to learning and relax the transformation of the world outlook, which is an important source that causes me to violate the bottom line of being a man today and embark on the road of violating discipline and law. The study of political theory, neither into the brain nor into the heart, mostly to complete the "task" in a formal way, the world outlook has not been transformed, how can it not be an accident? I didn’t change my worldview with the change of my post and the aggravation of my power, and I didn’t restrain my mind according to the requirements of party constitution’s party rules. I couldn’t strictly demand myself by the standards of a leading cadre. I went in the wrong direction, and the result was to go astray. During the 20-odd nights under investigation, I often dreamed of going home to see my mother at night. Her old man said the most words to me: "Girl, it’s not easy for you to get to today’s leadership position. Don’t take other people’s things." Such a simple truth, until now, I suddenly realized that I failed to keep the bottom line and distorted my values, which made me slip further and further on the wrong road.
The concept of power is gradually distorted, and the awareness of discipline and rules is weak.
Lack of awe of power. Looking back, I went from being bent on doing things, to making mistakes while doing things, and until today, I seriously violated discipline. This is a process from quantitative change to qualitative change. I am greedy for money, lack of awe for power, and always swear that I am honest and clean, which is self-deception. The reason why I have come to this point today is that apart from not studying for a long time, I have no fear of organization and power, and I am used to this kind of corruption. I always feel that as long as I don’t take the initiative to find someone, the nature will not be so bad. At this moment, sitting here and seriously reflecting, I think I should completely put down my worries and strive for organizational leniency. The person who can save me is still myself.
Weak sense of discipline and rules. Since the 18th National Congress of the Communist Party of China, the CPC Central Committee has repeatedly applied for the strict implementation of the spirit of the eight central regulations as the "first shot" to improve the style of cadres, but I turned a deaf ear to this. During the Spring Festival from 2014 to 2016, the gift cards sent by the relevant units and individuals were not rejected. Discipline was not taken as a ruler, discipline and rules were not put in front, and the high standards and strict requirements of leading cadres were not used to measure their actions. On the other hand, the root cause of one’s behavior and mistakes lies in not putting the word "strict" in every word and deed, and forgetting the purpose requirement of "power for the people".
Avoidance of organizational supervision, weak organizational concept
As a leading cadre, I should have high standards and strict requirements for myself, and I should do everything I say and do according to the disciplinary requirements. I, on the other hand, failed to report the real estate when I declared my major personal matters, and did not declare the real estate that I settled in my son’s early years on the grounds that my son worked independently in other places. In August 2014, when the stock market was good, I put almost all my savings and investment income at home into the stock market. Because of the large amount of funds, I was worried about being supervised by the organization, so I borrowed other people’s accounts to trade stocks, which were not truthfully declared in the personal affairs of leading cadres. According to common sense, it is only necessary to explain the source of funds when trading stocks in my own account. In order to avoid organizational supervision, I intentionally borrow other people’s accounts to trade stocks. This behavior is not strict with myself, avoiding organizational supervision, and showing a weak organizational concept. It was not until I was investigated that I found that many things I had done in the past were violations of discipline and discipline. I sincerely repent to the organization and really touch the depths of my mind and soul.
Break the bottom line of honesty, and go against the wind and violate discipline
Looking back, it was a process of being paralyzed and corroded that I became familiar with those business executives and even had economic exchanges. On holidays, I accept money and goods from some business owners, always thinking that everyone is an old acquaintance, and I have helped them. People call again and again, which is also true. If they don’t accept it, they feel embarrassed. It is this confused idea that has caused me to break the bottom line of honesty and self-discipline again and again and touch the red line that I shouldn’t touch. In the face of the investigation, I sincerely repent and deeply realize the mistakes I made. I hope that the organization can help me, so as to learn from the past and save lives, and let me be reborn.
Ignore the violation of discipline and have the illusion of luck.
Since August 2016, cadres Cheng Jiabin and Wang Guosheng of Ningguo Finance Bureau and Liu Faming, member of the Standing Committee of Ningguo Municipal Committee and executive deputy mayor, have been investigated successively. During this period, I also wanted to confess my fault to the organization, but in the end it was luck that hurt me, as shown in the following:
Don’t treat your mistakes correctly, and make them worse. This time, in investigating the case of Ningguo, I always reported my luck, waited and watched, did not treat my disciplinary actions correctly, did not actively confess to the organization, and added mistakes, deleted the mobile phone numbers of those corporate bosses stored in my mobile phone, entrusted others to call and say hello, and used collusion to cover up my corruption. In the face of investigation, it is an instinct to protect myself with this skill, but now it seems that it is not only ineffective, but also makes my wrong behavior worse. It’s really shocking to be investigated this time and reflect on your mistakes. Originally, I always stressed that I was influenced by the market economy development environment and didn’t reflect on my own problems. As everyone knows, internal factors are the key, and flies will not bite seamless eggs after all. Don’t study at ordinary times, do things dirty, and love takes advantage of small things, which will cause this situation today. In the face of the integrity of the comrades in the investigation team, I suddenly became so small, powerless and vulnerable.
I don’t have the courage to confess my mistakes to the organization and miss the opportunity. As a matter of fact, the organization gave me an opportunity several months ago, but I was stubborn and lucky. I didn’t take the initiative to confess my disciplinary behavior with the organization, and I made repeated mistakes and missed the opportunity. During the investigation, the comrades of the investigation team tried their best to enlighten me, educate me and help me, with the aim of saving me. Now, when I think of my intestines, I have to regret it. I want to cry, and I think of my family, but it is even more difficult to sleep and regret it.
I deeply feel the organization’s good intentions towards comrades who made mistakes. Although I confessed my mistakes to the organization, the pain in my heart will always exist. I am a cadre who has been trained by the organization for many years. I want to be loyal to the party. I don’t think I have developed to an irreparable level. I hope the organization can give me a chance to correct it.
During the period under investigation, I stayed up all night, seriously reflecting on my mistakes, and gradually changed from the original regret and self-blame to finding my own problems, and looking for reasons from the depths of my heart, the more I reflected on the lessons, the deeper I learned. I sincerely thank the organization for its educational help and the comrades of the investigation team for enlightening me, which gave me a chance to pull back from the brink. I’m not heinous and irreversible. I hope the organization will give me a chance to be reborn, and I will definitely repent and turn over a new leaf. At the same time, I will also take the initiative to hand over all illegal gains and strive for leniency. Think about the training of the organization, I feel deeply guilty, I am really sorry for the organization! Ask yourself, I have grown up to this day, which step is not the care and training of the organization? I still have deep feelings for the organization, hoping to get leniency from the organization.
I have little time to take care of my family members who have worked for me for a long time. I feel guilty when I think about it. My elderly mother, my unmarried son, my caring husband, my warm home. Mom, my daughter is unfilial!
related news
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Zhang Jiehui, deputy director of the Standing Committee of Hebei Provincial People’s Congress, was investigated for serious violation of discipline.
Illustration: Be alert! CPC Central Commission for Discipline Inspection has found more than ten new manifestations of the current "four winds" problem.
Liu Qiang, vice governor of Liaoning Province, was suspected of serious violation of discipline and accepted organizational review.
Lu Wei, former deputy director of the Propaganda Department of the CPC Central Committee, was suspected of serious violation of discipline and accepted organizational review.
Less than one month after the conclusion of the 19th National Congress, the "first tiger" was laid, and the anti-corruption struggle never stopped.
On August 23rd, Netease Cloud Music announced that it had officially reached a copyright cooperation agreement with Chris Lee, and more than 100 songs, including Chris Lee’s popular album Pop and Wow, will be launched on Netease Cloud Music. On August 26th, as the 18th anniversary of Chris Lee’s debut, his new song "Riding the Wind" will also be launched on Netease Cloud Music at 24: 00 on August 26th, bringing a heavy surprise to all "corn" in early autumn.
As a talented singer in Chinese music, Chris Lee has been loved by many fans since her debut. She has contributed many classic works to Chinese music and has a large number of loyal fans in Netease Cloud Music Station.
As the leading online music platform in China, Netease Cloud Music is very popular among music users in China. At the same time, Netease Cloud Music is also the most popular music platform for the younger generation in China. Its unique music community attribute can not only effectively improve the efficiency of music content distribution, but also help to enhance the influence of Chris Lee’s own music works among young users.
In 2022, Netease cloud music platform MAU reached 189 million, and daily users listened to songs for an average of 78.9 minutes. More than 33.4% of users listened to songs from the platform, which changed the traditional habit of listening to songs and created a highly viscous community interaction atmosphere.
Together, in addition to daily online content cooperation, Netease Cloud Music also used its own advantages in user operation and community atmosphere to innovatively create an offline creative interactive device of "See you at the next intersection" for Chris Lee. In Chengdu, Chris Lee’s hometown, Netease Cloud Music, with the yellow color of "corn" as the main tone and its masterpiece "See you at the next intersection" as the theme, laid interactive devices such as crossing graffiti, return street signs, corn road signs and telephone booths, attracting many fans and tourists to punch in. Let users not only listen to songs, but also participate in interesting interactions related to Chris Lee and enjoy more fun related to music.
In recent years, with the increasingly prominent advantages of unique community ecology and copyright operation ability, Netease Cloud Music has been favored by copyright parties at home and abroad. At present, many music companies at home and abroad have successively reached copyright cooperation on the platform. By the end of 2022, the total number of authorized music libraries was 116 million. Since 2021, Netease Cloud Music has successively reached copyright cooperation with Modern Sky, Hong Kong Emperor Entertainment, China Record Group, Lehua Entertainment, Fumao Records, SM Company, YG Entertainment, Times Fengjun, Yanshe, Avex, PonyCanyon, Believe Music and Rolling Stone Records. Songs of many famous artists, bands and musicians, such as Nicholas Tse, Joey Yung, Twins, New Pants, Tong Yang, Wu Tiao Ren, YiBo, Mayday, Greeny, Yu Ding Kui, were all lit up on Netease Cloud Music.
In the future, Netease Cloud Music will continue to actively promote cooperation with upstream copyright parties, and continuously provide more high-quality music content and better music consumption experience for China music lovers.
Disclaimer: This article is reprinted by our website, aiming to provide readers with more news information. The contents involved do not constitute investment and consumption suggestions, and are for readers’ reference only.
Original title: "Rock School": Rock is natural and unstoppable.
"Rock School" stills
This is an unstoppable world, because we are shouting together! This cry is not only the chorus of all the characters in the play, but also the collective applause and release of the audience. The Broadway musical "Rock School" has once again made the Tianqiao Art Center Grand Theater a grand carnival for opera fans.
The play tells the story of Dewey, the frustrated hero, who accidentally got the opportunity to start the children’s nature by rock and roll. It mocked the rigid education and the stubborn utilitarian values, and returned life to its original appearance. It seems that children’s interpretation is actually a topic that adults should reflect on.
To be fair, as far as the plot is concerned, the musical "Rock School" is an old-fashioned story in American campus dramas and film and television works, and some logic is not reasonable. However, after andrew lloyd webber’s magical musical expression and the wonderful performances of many outstanding actors, especially the elvish young actors, it has become different. The value collision reflected in the play, although it is a cliche, still has a strong realistic criticism in the new interpretation.
However, it is not so much a work that criticizes the shortcomings and values, but rather a masterpiece that explains the spirit of rock and roll. What is rock and roll? Not venting, not rebellion, not paranoia, not yelling! It is in the predicament of modern civilization that it is difficult to break through, and it sends out the voice of human beings for freedom and self-liberation. In the play, the rigid pragmatic education, which blindly pursues the ivy league enrollment rate, is the spokesman for people’s self-suppression and even strangulation of nature. In the fierce competition of contemporary commercial society, a successful life seems to be a solidified standard in the form of "consensus", but it ignores and obliterates individual differences, and even ignores the most basic rights of human beings-that is, human nature originates from nature, and some people run like wild horses like liger, while others like to migrate freely like antelopes and fly casually like birds. And rock and roll is to break the classical tradition, re-recognize ourselves, and restore nature by shouting and releasing.
After decades of smelting, Weber’s music has reached an insurmountable peak. This peak is not only for others, but also means a challenge to oneself. Although this latest work failed to make the expected breakthrough, the lyricism, melody and harmony based on rock and roll are beautiful and smooth, and the characters’ music is vivid, which still exquisitely demonstrates what dramatic music is. The incisiveness of rock and roll did not affect Weber’s reappearance of lyric unique skills, especially children’s solo, duet and chorus. Almost every paragraph was intoxicating and constantly won the cheers of the audience. However, the most amazing thing about Weber’s music is that it is particularly suitable for the characters and the situation. It seems that every note comes naturally from the heart with the plot and is properly on the "point".
Each character has a distinctive musical personality, and he also takes the opportunity to skillfully quote and borrow famous music passages familiar to the audience to highlight his character, and even makes fun of his most classic work "Memories". In the first scene of the music classroom, Luo Lisha, the principal, played stiff and boring classical music with her singing the famous aria after midnight in the opera The Magic Flute. The gorgeous aria of the original is obviously difficult to complete in the vocal range where the role is second to that of the female, but it is deliberately and forcibly reluctant. When it comes to the high notes, it has to pretend to be casually embarrassed or lowered by eight degrees, exposing the workplace and psychological embarrassment of the characters struggling. On a date in a bar, Luo Lisha was designed by Dewey. In his memory, he poured out his heart in the form of voice-changing rock, which formed a strong contrast in music color and further demonstrated the deep significance of rock’s liberation of human nature and inner spirit. I especially appreciate Luo Lisha’s handling of the aria "Where’s Rock and Roll?". She deliberately broke through her mellow timbre, and expressed her role in a wild and unrestrained state with a "sub-roar" singing style, which was very energetic and characteristic.
In my opinion, the overall shaping of Luo Lisha, the principal, is the most successful adult role in the play. What she has done, distorted by performance standards, is a pervert under the jungle law of ruthless business society. I have to put on airs for it, spilling a few drops of innocence from time to time, and the difference between inner and outer makes it very funny and cute. In the end, she resolutely put all her eggs in one basket for the rock of her true love, and gave Dewey a kiss, which symbolized that rock and roll washed away all obstacles.
Of course, the biggest difference of this drama is the collective amazement of the young actors. Their performances, especially their talent in shaping different characters, are extremely infectious. Whether it’s Shamei, a little girl who is a "band manager" with "leadership potential", Billy who wants to be a maverick stylist, or Zach, a guitarist who is always despised by his father, Tommy, who is afraid to express himself as the lead singer in the end, Lawrence, a keyboard player who is not confident but eager to be recognized, Freddie, a cool drummer, Katie, harmony sisters Marcy and Solana, etc., each child’s personality, temperament and emotional expression are extremely vivid and true. In contrast, our kind of children’s "art education", which is particularly good at creating a false and innocent national standard, is really embarrassing.
When Dewey’s "trick" broke through and came home frustrated, the children comforted and encouraged him and inspired his fighting spirit again. This bridge, if put in an adult performance, must be vulgar. However, this group of children actually let the "vulgar" be diluted in the pure singing, and eliminated the shortcomings in the sincerity. Tomika blurted out a well-known American work "God-given Grace" in a hurry. Although it did not reach the ideal preset state, it had a star-like charm and magnetic timbre, which was really rare. The boy Zach said, "Dad, can you really listen to me for once?" The weak but firm voice strongly stopped the father who "imposed his unfulfilled ideals on his children" and sublimated the topic of his own destiny. The subsequent children’s rock "Don’t compromise" pushed the whole drama to a climax without expectation.
In the seemingly regrettable but not regrettable ending, the ultimate idea of the play is revealed through Dewey’s mouth: the hard work in life is not to get ahead, but to make yourself the best and most enjoyable in countless possibilities. Real rock and roll lies in a kind of spirit, an original driving force of life, which comes from blood and faith, unstoppable and uncompromising! (Cheng Hui)
At present, there are factories in Tianjin that offer 24-degree palm oil at 7,000 yuan/ton, a slight increase of 50 yuan/ton compared with yesterday, and another factory that offers 24-degree palm oil at 6,950 yuan/ton. The transaction is negotiable. 8 degrees 7400 yuan/ton, 14 degrees 7350 yuan/ton, 18 degrees 7250 yuan/ton.
The spot market of 24-degree palm oil in Rizhao, Shandong Province reported about 6900 yuan/ton, which was basically the same as yesterday. Some factories quoted 6950 yuan/ton, so the transaction can be negotiated, and the willingness to make a transaction is not strong.
24-degree palm oil in Zhangjiagang, Jiangsu Province, the market price is 6950 yuan/ton, up by 50 yuan/ton compared with yesterday; The turnover of 10-degree palm oil was 7,200 yuan/ton (negotiable), up by 50 yuan/ton compared with yesterday; 14-degree palm oil is 7050 yuan/ton, which is flat.
The price of 24-degree palm oil market in Wuhan, Hubei Province is 7000-7050 yuan/ton, which is basically stable. The transaction can be negotiated and the transaction is average. 28 degrees 6650-6700 yuan/ton, 10 degrees 7250 yuan/ton, the transaction can be slightly lower. Keep it steady.
The price of 24-degree palm oil in Guangzhou was around 6750 yuan/ton, which basically remained stable and the market negotiated. The market importer quoted 6800-6850 yuan/ton, and the transaction was average.
